Prey was an amazing game when was released on PC and Xbox 360. After a painful development, the title offered a great vibe and a decent gunplay, but among those details I would like to stand out the organic ship and the crude treatment for some points of the story.
Human Head were developing a sequel, but sadly, was cancelled. Apparently, Bethesda had moved the development to Arkane Austin and nothing more was rumored in a long time.
According to Kotaku, Bethesda could unveil a new Prey at E3 2016. Arkane Austin could be working on a new Prey 2 (working title) very different from the Prey 2 developed by Human Head.
Kotaku have a great portfolio of rumors in the latest years. So, the rumor could be accurate.