Nintendo released The Legend of Zelda: The Twilight Princess almost simultaneously on two systems: Wii and GameCube. In this way, the Big N commercialized a big title in the Wii’s launch. NX could have a Zelda title in its launch.
According to SuperMetaldave64, Nintendo will launch Zelda U on NX. Nintendo could release this title along NX or within the launch window. Dave confirms NX for this 2016 as well.
SuperMetalDave64 claims this info is 100% accurate and comes from a direct source. In fact, his source and his information have been confirmed by NeoGAF mods.